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It has been shown that TRAP1 modified mitochondrial respiration and reprogrammed cellular metabolism (Yoshida et al., 2013)

Pharmaceutical Applications Glycyl-l-histidyl-l-lysine (GHK) is a tripeptide known for its high binding affinity to Cu 2+ and its complex role in wound healing

Vanharanta H, Ohnmeiss DD, Stith WJ, Regan JJ, Hochschuler SH, Guyer RD, Mooney V: The Effect of Repeated Trunk Extension and Flexion Movements as Seen By CT/Discography

Methods: MiR-126 mimics and inhibitors were transfected into M1 polarization macrophages RAW264.7 induced by LPS in vitro,Mertk and ADAM9 were detected by western blotting,inflammatory and anti-inflammatory cytokines were tested by qPCR.Apoptotic AML12 cells were added and co-cultured with the transfected macrophages,apoptosis related proteins were detected by Western Blotting,efferocytosis/phagocytosis index were observed by fluorescence microscope.Finally,miR-126 loaded into the exosomes of mesenchymal stem cells co-cultured with M1 polarization macrophages,efferocytosis index and the expression of related signaling pathway proteins were detected

Cell Mol Life Sci 82:147